Active Ingredient History
Golimumab, sold under the brand name Simponi, is a human monoclonal antibody which is used as an immunosuppressive medication. Golimumab targets tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory molecule and hence is a TNF inhibitor. Profound reduction in C-reactive protein (CRP) levels, interleukin (IL)-6, intercellaular adhesion molecules (ICAM)-1, matrix metalloproteinase (MMP)-3, and vascular endothelial growth factor (VEGF) demonstrates golimumab as an effective modulator of inflammatory markers and bone metabolism. Golimumab is given via subcutaneous injection. Wikipedia
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Arthritis (Phase 3)
Arthritis, Juvenile (Phase 3)
Asthma (Phase 2)
Autoimmune Diseases (Phase 3)
Axial Spondyloarthritis (Phase 4)
Behcet Syndrome (Phase 2)
Colitis (Phase 4)
Crohn Disease (Phase 4)
Diabetes Mellitus, Type 1 (Phase 2)
Drug Combinations (Phase 4)
Fibrosis (Phase 3)
Healthy Volunteers (Phase 1)
Inflammatory Bowel Diseases (Phase 4)
Lymphoma, T-Cell (Phase 4)
Methotrexate (Phase 4)
Prostatic Neoplasms (Phase 2)
Sarcoidosis (Phase 2)
Spondylarthropathies (Phase 4)
Substance Withdrawal Syndrome (Phase 3)
Thromboembolism (Phase 4)
Uveitis (Phase 2)
| Trial | Phase | Start Date | Organizations | Indications |
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