API | durlobactam

durlobactam (Xacduro) Report issue

Small molecule Approved ^FDA Fast Track ^FDA Priority Review ^FDA

Active Ingredient History

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Chemistry

SMILES: CC1=C[C@@H]2CN(C(=O)N2OS(=O)(=O)[O-])[C@@H]1C(N)=O.[Na+]
InChIKey: WHHNOICWPZIYKI-IBTYICNHSA-M
Mol. Mass: 299.24
ALogP: -1.36 Partition coefficient
ChEMBL Molecules:

durlobactam sodium

durlobactam

More Chemistry

Pharmacology

Mechanisms of Action:
- Beta-lactamase (Acinetobacter baumannii) ^UniProt
- Beta-lactamase (Acinetobacter calcoaceticus) ^UniProt
- Beta-lactamase (Acinetobacter genomosp. 3) ^UniProt
- Beta-lactamase (Acinetobacter nosocomialis) ^UniProt
- Beta-lactamase (Acinetobacter baumannii) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Prescription Only
Delivery Methods: Parenteral
Pro Drug: No

Combination drugs

xacduro (copackaged) ( sulbactam (unasyn), durlobactam (Xacduro) - other name: sulbactam-durlobactam (sul-dur) )

Organizations (2)

Research & Development (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (2)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (1)

Approved Indications (1)

Pneumonia (approved 2023)

Experimental Indications - Clinical Trial Phases 1-4 (0)

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