quinapril (accupril) Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

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Quinapril is the hydrochloride salt of quinapril, the ethyl ester of a non-sulfhydryl, angiotensin-converting enzyme (ACE) inhibitor, quinaprilat. Quinapril hydrochloride is a white to off-white amorphous powder that is freely soluble in aqueous solvents. Quinapril is indicated for the treatment of high blood pressure (hypertension) and as adjunctive therapy in the management of heart failure. It may be used for the treatment of hypertension by itself or in combination with thiazide diuretics, and with diuretics and digoxin for heart failure.   NCATS

Chemistry

More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: Yes

Drug Pricing (per unit)

Australia

$0.0858 - $0.2117

United States

$0.1027 - $3.1308
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

( hydrochlorothiazide (esidrix), quinapril (accupril) )

Alternative names

2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid | 3-isoquinolinecarboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, monohydrochloride, (3s-(2(r*(r*)),3r*))- | accupril | accupro | ci 906 | ci-906 | ectren | koretic | pd 109452-2 | pd-109,452-2 | qualaquin | quinapril | quinaprilat | quinapril hcl | quinapril hydrochloride | quinaprilum | quinil

Organizations (58)

Research & Development (47)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (13)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (23)

Approved Indications (5)


 

Diabetes Mellitus

Heart Failure

Hypertension

Renal Insufficiency

Stroke

Experimental Indications - Clinical Trial Phases 1-4 (20)


 

Atrial Fibrillation (Phase 4)

Cardiovascular Diseases (Phase 4)

Coronary Artery Bypass (Phase 4)

Diabetes Mellitus, Type 1 (Phase 3)

Diabetes Mellitus, Type 2 (Phase 4)

Diabetic Neuropathies (Phase 4)

Essential Hypertension (Phase 4)

Glomerulonephritis, IGA (Phase 4)

Healthy Volunteers (Phase 1)

Heart Diseases (Phase 4)

Hypertension (Phase 4)

Hypotension (Phase 4)

Immunosuppression Therapy (Phase 4)

Lupus Erythematosus, Systemic (Phase 4)

Menopause (Phase 4)

Multiple Myeloma (Phase 1)

Myocardial Ischemia (Phase 4)

Prostatic Hyperplasia (Phase 4)

Renal Insufficiency, Chronic (Phase 4)

Stroke (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 30
  • # of Trial Organizations: 47

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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