linolic acid Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central MeSH PubChem

Active Ingredient History

NOW
  • Now
Linoleic acid (LA) is an organic compound with the formula HOOC(CH2)7CH=CHCH2CH=CH(CH2)4CH3. Both alkene groups are cis. It is a fatty acid sometimes denoted 18:2 (n-6) or 18:2 cis-9,12. A linoleate is a salt or ester of this acid.   Wikipedia

Chemistry

  • SMILES: CCCCC/C=C\C/C=C\CCCCCCCC(=O)O
  • InChIKey: OYHQOLUKZRVURQ-HZJYTTRNSA-N
  • Mol. Mass: 280.45
  • ALogP: 5.88
  • ChEMBL Molecules:
    linoleic acid  
    linolenic acid  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

(9,12,15)-linolenic acid | 9,12,15-octadecatrienoic acid | 9-cis,12-cis,15-cis-octadecatrienoic acid | (9z,12z,15z)-octadecatrienoic acid | ala | alfa-linolenic acid | all-cis-9,12,15-octadecatrienoic acid | alpha-linoleic acid | alpha linolenic acid | alpha-linolenic acid | cis,cis,cis-9,12,15-octadecatrienoic acid | cis-delta(9,12,15)-octadecatrienoic acid | linoleic acid | linolenate | linolenic acid | linolic acid | (z,z,z)-9,12,15-octadecatrienoic acid | α-linolenic acid

Organizations (22)

Research & Development (22)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (13)

Approved Indications (1)


 

Cardiovascular Diseases

Experimental Indications - Clinical Trial Phases 1-4 (12)


 

Atherosclerosis (Phase 2)

Carcinoma, Basal Cell (Phase 2)

Dyslipidemias (Phase 1/Phase 2)

Healthy Volunteers (Phase 4)

Hypercholesterolemia (Phase 3)

Inflammation (Phase 3)

Multiple Sclerosis (Phase 1)

Neuroaxonal Dystrophies (Phase 2/Phase 3)

Nutritional and Metabolic Diseases ()

Obesity (Phase 1/Phase 2)

Obesity, Morbid (Phase 2)

Sarcopenia (Phase 3)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 17
  • # of Trial Organizations: 22

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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