tetrahydrouridine Report issue

Small molecule Experimental
AACT DrugBank PubChem

Active Ingredient History

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Chemistry

  • SMILES: O=C1N[C@H](O)CCN1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
  • InChIKey: UCKYOOZPSJFJIZ-FMDGEEDCSA-N
  • Mol. Mass: 248.24
  • ALogP: -2.84
  • ChEMBL Molecule:
    tetrahydrouridine  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

tetrahydrouridine

Organizations (9)

Research & Development (9)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (21)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (21)


 

Anemia, Sickle Cell (Phase 2)

Brain Neoplasms (Phase 1)

Breast Neoplasms (Phase 2)

Carcinoma, Non-Small-Cell Lung (Phase 2)

Esophageal Neoplasms (Phase 1/Phase 2)

Head and Neck Neoplasms (Phase 2)

Healthy Volunteers (Phase 1)

Leukemia, Myeloid, Acute (Phase 1)

Lung Neoplasms (Phase 2)

Lymphoma, B-Cell (Early Phase 1)

Lymphoma, Non-Hodgkin (Early Phase 1)

Lymphoma, T-Cell (Early Phase 1)

Melanoma (Phase 1)

Mesothelioma, Malignant (Phase 1/Phase 2)

Myelodysplastic Syndromes (Phase 1)

Neoplasm Metastasis (Phase 1)

Neoplasms (Phase 1)

Neoplasms, Germ Cell and Embryonal (Phase 1)

Pancreatic Neoplasms (Early Phase 1)

Sarcoma (Phase 1)

Urinary Bladder Neoplasms (Phase 2)

Overview

  • Highest Phase: Phase 2
  • # of Trials: 14
  • # of Trial Organizations: 9

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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