API | amsacrine

amsacrine Report issue

Small molecule Experimental

AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

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Chemistry

SMILES: COc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2ccccc12
InChIKey: XCPGHVQEEXUHNC-UHFFFAOYSA-N
Mol. Mass: 393.47
ALogP: 4.51 Partition coefficient
ChEMBL Molecule:
amsacrine

More Chemistry

Pharmacology

Mechanism of Action:
- DNA topoisomerase 2-alpha (Homo sapiens) ^UniProt
- DNA topoisomerase 2-beta (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Parenteral
Pro Drug: No

4'-(9-acridinylamino)-3'-methoxymethanesulfonanilide | 4'-(9-acridinylamino)methanesulfon-m-anisidide | 4'-(9-acridinylamino)methanesulfon-meta-anisidide | 4'-(9-acridinylamino)methanesulphon-m-anisidide | acridinylanisidide | acridinyl anisidide | amekrin | amsacrine | amsidil | amsidine | amsidyl | ci-880 | lamasine | mamsa | m-amsa | nci-249992

Organizations (16)

Research & Development (16)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (6)

Approved Indications (1)

Experimental Indications - Clinical Trial Phases 1-4 (6)

Leukemia (Phase 3)

Leukemia, Myeloid, Acute (Phase 4)

Leukemia, Myelomonocytic, Chronic (Phase 1/Phase 2)

Myelodysplastic Syndromes (Phase 3)

Neutropenia (Phase 3)

Overview

Highest Phase: Phase 4
# of Trials: 10
# of Trial Organizations: 16

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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