strontium ranelate (Protelos) Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Strontium ranelate, a strontium(II) salt of ranelic acid, is a medication for osteoporosis marketed as Protelos or Protos by Servier. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both increases deposition of new bone by osteoblasts and reduces the resorption of bone by osteoclasts. It is therefore promoted as a "dual action bone agent" (DABA).   Wikipedia

Chemistry

  • SMILES: N#Cc1c(N(CC(=O)[O-])CC(=O)[O-])sc(C(=O)[O-])c1CC(=O)[O-].[Sr+2].[Sr+2]
  • InChIKey: XXUZFRDUEGQHOV-UHFFFAOYSA-J
  • Mol. Mass: 513.49
  • ALogP: -0.08
  • ChEMBL Molecule:
    strontium ranelate  
More Chemistry

Pharmacology

  • Mechanisms of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

3-(3-cyano-4-carboxymethyl-5-carboxy-2-thienyl)-3-azapentanedioic distrontium salt | bivalos | distrontium renelate | osseor | protelos | s12911 | s 12911 | s-12911 | s12911-0 | s12911-2 | s12911-5 | strontium ranelate

Organizations (7)

Research & Development (7)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (7)

Approved Indications (1)


 

Osteoporosis

Experimental Indications - Clinical Trial Phases 1-4 (7)


 

Bone Diseases, Metabolic (Phase 4)

Clinical Trial (Phase 4)

Compliance (Phase 4)

Fractures, Bone (Phase 4)

Hyperparathyroidism, Primary (Phase 4)

Osteoporosis (Phase 4)

Osteoporosis, Postmenopausal (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 6
  • # of Trial Organizations: 7

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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