sertindole (Serdolect) Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Sertindole, sold under the brand name Serdolect among others, is an antipsychotic medication. Sertindole was developed by the Danish pharmaceutical company Lundbeck and marketed under license by Abbott Labs. Like other atypical antipsychotics, it has activity at dopamine and serotonin receptors in the brain. It is used in the treatment of schizophrenia. It is classified chemically as a phenylindole derivative.   Wikipedia

Chemistry

  • SMILES: O=C1NCCN1CCN1CCC(c2cn(-c3ccc(F)cc3)c3ccc(Cl)cc23)CC1
  • InChIKey: GZKLJWGUPQBVJQ-UHFFFAOYSA-N
  • Mol. Mass: 440.95
  • ALogP: 4.63
  • ChEMBL Molecule:
    sertindole  
More Chemistry

Pharmacology

Alternative names

1-(2-(4-(5-chloro-1-(4-fluorophenyl)-1h-indol-3-yl)-1-piperidinyl)ethyl)-2-imidazolidinone | 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one | lu 23-174 | lu-23-174 | serdolect | serlect | sertindol | sertindole | sertindole hcl | sertindole hydrochloride | sertindolum | zerdol

Organizations (13)

Research & Development (13)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (9)

Approved Indications (1)


 

Schizophrenia

Experimental Indications - Clinical Trial Phases 1-4 (9)


 

Anxiety Disorders (Phase 3)

Cognition (Phase 3)

Dementia (Phase 3)

Depression (Phase 3)

Mental Health (Phase 3)

Psychophysiologic Disorders (Phase 3)

Psychotic Disorders (Phase 4)

Schizophrenia (Phase 4)

Schizophrenia Spectrum and Other Psychotic Disorders (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 16
  • # of Trial Organizations: 13

Trials by Phase

Trial Phase Start Date Organizations Indications

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