API | amdoxovir

amdoxovir Report issue

Small molecule Experimental

AACT ChEMBL MeSH PubChem

Active Ingredient History

NOW

Amdoxovir is a pharmaceutical drug that has undergone research for the treatment of HIV/AIDS. It acts as a nucleoside reverse transcriptase inhibitor (NRTI). The drug was discovered by Raymond F. Schinazi and C.K. Chu and developed by RFS Pharma. ^Wikipedia

Chemistry

SMILES: Nc1nc(N)c2ncn([C@H]3CO[C@@H](CO)O3)c2n1
InChIKey: RLAHNGKRJJEIJL-RFZPGFLSSA-N
Mol. Mass: 252.23
ALogP: -1.15 Partition coefficient
ChEMBL Molecule:
amdoxovir

More Chemistry

Pharmacology

Mechanisms of Action:
- Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) ^UniProt
- Reverse transcriptase (Human immunodeficiency virus 2) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

2,6-diaminopurine dioxolane | 4-(2,6-diamino-9h-purin-9-yl)-1,3,-dioxolane-2-methanol | amdoxovir | dapd | (-)-dapd

Organizations (6)

Research & Development (6)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (2)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (2)

HIV (Phase 2)

HIV Infections (Phase 2)

Overview

Highest Phase: Phase 2
# of Trials: 5
# of Trial Organizations: 6

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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