OCTAMYLAMINE (octinum) Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Isometheptene (usually as isometheptene mucate) is a sympathomimetic amine sometimes used in the treatment of migraines and tension headaches due to its vasoconstricting properties. Isometheptene's vasoconstricting properties arise through activation of the sympathetic nervous system via epinephrine and norepinephrine. These compounds elicit smooth muscle activation leading to vasoconstriction by interacting with cell surface adrenergic receptors.   NCATS

Chemistry

  • SMILES: CNC(C)CCC=C(C)C
  • InChIKey: XVQUOJBERHHONY-UHFFFAOYSA-N
  • Mol. Mass: 141.2539
  • ALogP: 2.34
  • ChEMBL Molecules:
    isometheptene  
    None  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

6-methylamino-2-methylheptene | isometeptene | isomethepten | isometheptene | isometheptene, (+-)-isomer | isometheptene, maleate | isometheptene, maleate(+-)-isomer | isometheptene monohydrochoride | isometheptene, monomaleate | isometheptene, monomaleate(+-)-isomer | isometheptene, monotartrate | isometheptene mucate | isometheptene, mucate (2:1) | midrid | n,1,5-trimethyl-4-hexenylamine | n,6-dimethyl-5-hepten-2-amine | octinum

Organizations (2)

Research & Development (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (4)

Approved Indications (3)


 

Headache

Migraine Disorders

Neuralgia

Experimental Indications - Clinical Trial Phases 1-4 (2)


 

Healthy Volunteers (Phase 1)

Migraine Disorders (Phase 3)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 2
  • # of Trial Organizations: 2

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue