Active Ingredient History
Platelet-rich fibrin (PRF) or leukocyte- and platelet-rich fibrin (L-PRF) is a derivative of PRP where autologous platelets and leukocytes are present in a complex fibrin matrix to accelerate the healing of soft and hard tissue and is used as a tissue-engineering scaffold in oral and maxillofacial surgeries. PRF falls under FDA Product Code KST, labeling it as a blood draw/Hematology product classifying it as 510(k) exempt. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Aging (Phase 1/Phase 2)
Alopecia (Phase 3)
Alveolar Bone Loss (Phase 2)
Anastomotic Leak (Phase 2/Phase 3)
Blood Platelets (Phase 4)
Bone and Bones (Phase 4)
Bone Density (Phase 2)
Bone Diseases (Early Phase 1)
Bone Regeneration (Phase 4)
Bone Resorption (Phase 3)
Bone Substitutes (Phase 4)
Chronic Periodontitis (Phase 4)
Colorectal Surgery (Phase 2/Phase 3)
Dental Implantation, Endosseous (Phase 2)
Dental Implants (Phase 1)
Dental Pulp (Phase 1/Phase 2)
Dental Pulp Necrosis (Phase 2)
Diabetes Mellitus (Early Phase 1)
Diabetic Foot (Early Phase 1)
Dupuytren Contracture (Phase 2/Phase 3)
Erectile Dysfunction (Phase 3)
Eye Diseases, Hereditary (Early Phase 1)
Furcation Defects (Phase 4)
Gingival Diseases (Phase 4)
Infections (Phase 1)
Inflammation (Phase 3)
Low Back Pain (Phase 4)
Lung (Phase 4)
Maxillary Sinus (Phase 4)
Nasolabial Fold (Phase 1/Phase 2)
Neoplasms (Phase 1)
Osteoarthritis (Phase 2/Phase 3)
Periodontal Diseases (Phase 4)
Periodontal Pocket (Phase 1)
Periodontitis (Phase 4)
Platelet-Rich Fibrin (Phase 4)
Pulpitis (Phase 4)
Temporomandibular Joint Disorders (Phase 2/Phase 3)
Tooth (Phase 1/Phase 2)
Tooth Abnormalities (Phase 2)
Tooth Fractures (Phase 1)
Tooth Loss (Phase 2)
Ulcer (Phase 1)
Wounds and Injuries (Phase 2/Phase 3)
| Trial | Phase | Start Date | Organizations | Indications |
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