API | pexacerfont

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Small molecule Experimental

AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

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Pexacerfont (INN, previously known as BMS-562,086) is a drug developed by Bristol-Myers Squibb which acts as a CRF1 antagonist. ^Wikipedia

Chemistry

SMILES: CC[C@@H](C)Nc1nc(C)nc2c(-c3ccc(OC)nc3C)c(C)nn12
InChIKey: LBWQSAZEYIZZCE-SNVBAGLBSA-N
Mol. Mass: 340.43
ALogP: 3.33 Partition coefficient
ChEMBL Molecule:
pexacerfont

More Chemistry

Pharmacology

Mechanism of Action:
- Corticotropin-releasing factor receptor 1 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

bms-562086 | crf1 antagonist | pexacerfont

Organizations (3)

Research & Development (3)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (7)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (7)

Alcoholism (Phase 2)

Alcohol-Related Disorders (Phase 2)

Anxiety Disorders (Phase 2/Phase 3)

Depressive Disorder, Major (Phase 1/Phase 2)

Drugs, Investigational (Early Phase 1)

Irritable Bowel Syndrome (Phase 2)

Placebos (Early Phase 1)

Overview

Highest Phase: Phase 3
# of Trials: 5
# of Trial Organizations: 3

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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