API | kallikrein

kallikrein Report issue

Biological Experimental

AACT PubChem

Active Ingredient History

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Kallikreins are a subgroup of serine proteases, enzymes capable of cleaving peptide bonds in proteins. In humans, plasma kallikrein has no known paralogue, while tissue kallikrein-related peptidases (KLKs) encode a family of fifteen closely related serine proteases. These genes are localised to chromosome 19q13, forming the largest contiguous cluster of proteases within the human genome. Kallikreins are responsible for the coordination of various physiological functions including blood pressure, semen liquefaction and skin desquamation. ^Wikipedia

Chemistry

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Pharmacology

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kallikrein

Organizations (4)

Research & Development (4)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (7)

Approved Indications (1)

Diagnosis

Experimental Indications - Clinical Trial Phases 1-4 (6)

Brain Infarction (Phase 4)

Cerebral Infarction (Phase 4)

Collateral Circulation (Phase 4)

Hereditary Angioedema Types I and II ()

Intracranial Arteriosclerosis (Phase 4)

Stroke (Phase 4)

Overview

Highest Phase: Phase 4
# of Trials: 3
# of Trial Organizations: 4

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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