API | brecanavir

brecanavir Report issue

Small molecule Experimental

AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

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Brecanavir is a protease inhibitor which has been studied for the treatment of HIV. ^Wikipedia

Chemistry

SMILES: Cc1nc(COc2ccc(C[C@H](NC(=O)O[C@H]3CO[C@H]4OCC[C@H]43)[C@H](O)CN(CC(C)C)S(=O)(=O)c3ccc4c(c3)OCO4)cc2)cs1
InChIKey: JORVRJNILJXMMG-OLNQLETPSA-N
Mol. Mass: 703.84
ALogP: 3.87 Partition coefficient
ChEMBL Molecule:
brecanavir

More Chemistry

Pharmacology

Mechanisms of Action:
- HIV-1 protease (Human immunodeficiency virus) ^UniProt
- Pol polyprotein (Human immunodeficiency virus 1) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

(1s,2r)-3-((1,3-benzodioxol-5-ylsulfonyl)(2-methylpropyl)amino-2-hydroxy-1-((4-(2-methyl-4-thiazolyl)methoxy)phenyl)methylpropyl)carbamic acid, hexahydrofuro(2,3-b)furan-3yl ester | bcv | brecanavir | gw640385 | gw64085x | vx385 | vx-385

Organizations (2)

Research & Development (2)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (2)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (2)

HIV (Phase 2)

HIV Infections (Phase 2)

Overview

Highest Phase: Phase 2
# of Trials: 2
# of Trial Organizations: 2

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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