guadecitabine Report issue

Small molecule Experimental
AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

NOW
  • Now

Chemistry

  • SMILES: Nc1ncn([C@H]2C[C@H](OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(=O)[nH]c(N)nc54)C[C@@H]3O)[C@@H](CO)O2)c(=O)n1
  • InChIKey: GUWXKKAWLCENJA-WGWHJZDNSA-N
  • Mol. Mass: 557.42
  • ALogP: -2.63
  • ChEMBL Molecule:
    guadecitabine  
More Chemistry

Pharmacology

Alternative names

guadecitabine | sgi-110

Organizations (30)

Research & Development (30)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (30)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (30)


 

Bile Duct Neoplasms (Phase 1)

Carcinoma, Hepatocellular (Phase 2)

Carcinoma, Non-Small-Cell Lung (Phase 2)

Carcinoma, Renal Cell (Phase 2)

Carcinoma, Transitional Cell (Phase 2)

Cholangiocarcinoma (Phase 1)

Chondrosarcoma (Phase 2)

Colorectal Neoplasms (Phase 1/Phase 2)

Fallopian Tube Neoplasms (Phase 2)

Gallbladder Neoplasms (Phase 1)

Gastrointestinal Stromal Tumors (Phase 2)

Hamartoma (Phase 2)

Kidney Neoplasms (Phase 2)

Leukemia, Myeloid, Acute (Phase 3)

Leukemia, Myelomonocytic, Chronic (Phase 3)

Lung Neoplasms (Phase 1)

Melanoma (Phase 2)

Methylation (Phase 1/Phase 2)

Myelodysplastic Syndromes (Phase 3)

Myeloproliferative Disorders (Phase 2)

Neoplasm, Residual (Phase 2)

Neoplasms ()

Neoplasms, Germ Cell and Embryonal (Phase 1)

Ovarian Neoplasms (Phase 2)

Pancreatic Neoplasms (Phase 1)

Paraganglioma (Phase 2)

Pheochromocytoma (Phase 2)

Prostatic Neoplasms, Castration-Resistant (Phase 1)

Small Cell Lung Carcinoma (Phase 2)

Testicular Neoplasms (Phase 1)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 33
  • # of Trial Organizations: 30

Trials by Phase

Trial Phase Start Date Organizations Indications

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