Active Ingredient History
Rapastinel is a novel antidepressant that was under development by Allergan as an adjunctive therapy for the treatment of treatment-resistant depression. It is a centrally active, intravenously administered amidated tetrapeptide that acts as a novel and selective modulator of the NMDA receptor. The drug is a rapid-acting and long-lasting antidepressant as well as robust cognitive enhancer by virtue of its ability to enhance NMDA receptor-mediated signal transduction and synaptic plasticity. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Automobile Driving (Phase 1)
Cognition ()
Depression ()
Depressive Disorder, Major (Phase 3)
Healthy Volunteers (Phase 2)
Memory Disorders (Phase 2)
Mental Disorders (Phase 2)
Obsessive Behavior (Phase 2)
Substance Abuse, Oral (Phase 1)
| Trial | Phase | Start Date | Organizations | Indications |
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