Active Ingredient History

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Gadoteric acid, sold under the brand name Dotarem among others, is a macrocycle-structured gadolinium-based MRI contrast agent (GBCA). It consists of the organic acid DOTA as a chelating agent, and gadolinium (Gd3+), and is used in form of the meglumine salt (gadoterate meglumine). The paramagnetic property of gadoteric acid reduces the T1 relaxation time (and to some extent the T2 and T2* relaxation times) in MRI, which is the source of its clinical utility. Because it has magnetic properties, gadoteric acid develops a magnetic moment when put under a magnetic field, which increases the signal intensity (brightness) of tissues during MRI imaging.   Wikipedia

More Chemistry
  • Mechanisms of Action: Missing data
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Parenteral
  • Pro Drug: No

Drug Pricing (per unit)

United States

$9.3740 - $119.9933
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

[2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl-κ4n1,n4,n7,n10)tetraacetato(3−)]gadolinium | dota-gd | dotarem | gadolinate(1-), (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetato(4-)- | gadolinium 1,4,7,10-tetraazacyclododecane-n,n',n'',n'''-tetraacetate | gadolinium dota | gadoterate | gadoterate dimeglumine | gadoterate meglumine | gadoterate sodium | gadoteric acid | gd-dota | gd-dota meglumine | magnescope | meglumine gadoterate | p-449

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