flucloxacillin Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Flucloxacillin, also known as floxacillin, is an antibiotic used to treat skin infections, external ear infections, infections of leg ulcers, diabetic foot infections, and infection of bone. It may be used together with other medications to treat pneumonia, and endocarditis. It may also be used prior to surgery to prevent Staphylococcus infections. It is not effective against methicillin-resistant Staphylococcus aureus (MRSA). It is taken by mouth or given by injection into a vein or muscle.   Wikipedia

Chemistry

  • SMILES: Cc1onc(-c2c(F)cccc2Cl)c1C(=O)N[C@@H]1C(=O)N2[C@@H]1SC(C)(C)[C@@H]2C(=O)O
  • InChIKey: UIOFUWFRIANQPC-JKIFEVAISA-N
  • Mol. Mass: 453.88
  • ALogP: 2.69
  • ChEMBL Molecule:
    floxacillin  
More Chemistry

Pharmacology

Drug Pricing (per unit)

Australia

$0.1379 - $7.1328
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Alternative names

(2s,5r,6r)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid | 3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillin | abboflox | brl-2039 | floxacillin | floxapen | fluclomix-250 | fluclomix-500 | flucloxacilina | flucloxacillin | flucloxacilline | flucloxacillin sodium | flucloxacillinum | flucloxin | fluocloxacilin | fluoxacillin | galfloxin | ladropen | rimaflox | stafoxil | staphlipen | zoxin 250 | zoxin 500

Organizations (25)

Research & Development (25)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (14)

Approved Indications (1)


 

Bacterial Infections

Experimental Indications - Clinical Trial Phases 1-4 (14)


 

Abscess (Phase 4)

Bacterial Infections (Phase 1)

Cellulitis (Phase 4)

Drug Interactions (Phase 1)

Erysipelas (Phase 4)

Healthy Volunteers (Phase 1)

Infections (Phase 2)

Osteomyelitis (Phase 2)

Renal Insufficiency, Chronic (Phase 1)

Skin Diseases, Bacterial (Phase 3)

Skin Diseases, Infectious (Phase 3)

Staphylococcal Infections (Phase 3)

Staphylococcus aureus (Phase 4)

Wound Infection (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 14
  • # of Trial Organizations: 25

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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