API | Caroverine

Caroverine (spadon) Report issue

Small molecule Experimental

AACT ChEMBL Drug Central KEGG PubChem

Active Ingredient History

NOW

Caroverine is a muscle-relaxing drug used in Austria and Switzerland to relieve spasms in smooth muscles, and the use in those countries was extended to aid with cerebrovascular diseases there, and eventually to treat tinnitus. It is also used to treat tinnitus in India. ^Wikipedia

Chemistry

SMILES: CCN(CC)CCn1c(=O)c(Cc2ccc(OC)cc2)nc2ccccc21
InChIKey: MSPRUJDUTKRMLM-UHFFFAOYSA-N
Mol. Mass: 365.48
ALogP: 3.34 Partition coefficient
ChEMBL Molecule:
caroverine

More Chemistry

Pharmacology

Mechanism of Action:
- Glutamate receptor ionotropic, NMDA 3A (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

caroverin | caroverine | spadon

Organizations (2)

Research & Development (2)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (1)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (1)

Tinnitus (Phase 3)

Overview

Highest Phase: Phase 3
# of Trials: 1
# of Trial Organizations: 2

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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