thorium dioxide Report issue

Small molecule Approved
PubChem

Active Ingredient History

NOW
  • Now
Thorium dioxide, a main component of Thorotrast that was used as a contrast agent for cerebral angiography. Thorotrast is an alpha emitter and primary site of deposition is the reticuloendothelial system including the liver, spleen, bone marrow, and lymph nodes. However was discovered, that this compound can cause hepatic angiosarcoma with a long latent period. That is why this contrast agent was withdrawn.   NCATS

Chemistry

  • SMILES: [O--].[O--].[Th+4]
  • InChIKey: DNNLEMIRRGUGOZ-UHFFFAOYSA-N
  • Mol. Mass: 264.0369
  • ALogP: Missing data
  • ChEMBL Molecules: Missing data
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Missing data
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: Missing data

Alternative names

colloidal thorium | thorotrast

Indications (1)

Approved Indications (1)


 

Diagnostic Imaging (approved 1928)

Experimental Indications - Clinical Trial Phases 1-4 (0)

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