API | 4-hydroxyifosfamide

4-hydroxyifosfamide Report issue

Small molecule Experimental

Active Ingredient History

Ifosfamide (IF) is a widely used antitumor prodrug. It is in the oxazaphosphorine class of alkylating agents, and it is effective against solid tumors. Ifosfamide mechanism of crosslinking DNA plays a major role in preventing cancer cells from proliferating. Ifosfamide is approved by FDA for the treatment of germ cell testicular cancer. ^NCATS

Chemistry

SMILES: OC1CCOP(=O)(NCCCl)N1CCCl
InChIKey: JHUJMHKRHQPBRG-UHFFFAOYSA-N
Mol. Mass: 277.085
ALogP: Missing data
ChEMBL Molecules: Missing data

More Chemistry

Pharmacology

Mechanisms of Action: Missing data
Multi-specific: Missing data
Black Box: Missing data
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: Missing data

Indications (1)

Approved Indications (1)

Testicular Neoplasms (approved 1988)

Experimental Indications - Clinical Trial Phases 1-4 (0)

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