API | stibocaptate

stibocaptate Report issue

Small molecule Experimental

Active Ingredient History

Succimer is an analogue of dimercaprol, and has replaced dimercaprol as one of the main antidotes used in the management of poisoning by lead and other heavy metals. The advantages of succimer are that it is effective by oral administration because it is soluble in water, it is well-tolerated, has relatively low toxicity and can be given at the same time as iron supplements to treat iron deficiency anaemia. It does not cause significant increase in urinary excretion of essential minerals unlike the other widelyused lead chelating agent, sodium calcium EDTA. ^NCATS

Chemistry

SMILES: OC(=O)C(S[Sb]1SC(C(S1)C(O)=O)C(O)=O)C(S[Sb]2SC(C(S2)C(O)=O)C(O)=O)C(O)=O
InChIKey: WRIDGMJGKDWAJY-UHFFFAOYSA-H
Mol. Mass: 784.126
ALogP: Missing data
ChEMBL Molecules: Missing data

More Chemistry

Pharmacology

Mechanisms of Action: Missing data
Multi-specific: Missing data
Black Box: Missing data
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: Missing data

Indications (1)

Approved Indications (1)

Lead Poisoning (approved 1993)

Experimental Indications - Clinical Trial Phases 1-4 (0)

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