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Small molecule Experimental

Active Ingredient History

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Chemistry

SMILES: C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n1-c1ccc2c(n1)[C@@](O)(CC)CC2
InChIKey: OXTSYWDBUVRXFF-GDLZYMKVSA-N
Mol. Mass: 526.65
ALogP: 3.2 Partition coefficient
ChEMBL Molecule:
azenosertib

More Chemistry

Pharmacology

Mechanism of Action:
- Wee1-like protein kinase (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

Organizations (8)

Research & Development (8)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (17)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (17)

Breast Neoplasms (Phase 1/Phase 2)

Carcinoma, Non-Small-Cell Lung (Phase 1/Phase 2)

Carcinoma, Ovarian Epithelial (Phase 1/Phase 2)

Carcinoma, Transitional Cell (Phase 1/Phase 2)

Colorectal Neoplasms (Phase 1/Phase 2)

Fallopian Tube Neoplasms (Phase 1/Phase 2)

Hamartoma (Phase 1/Phase 2)

Leukemia, Myeloid, Acute (Phase 1/Phase 2)

Lung Neoplasms (Phase 1)

Melanoma (Phase 1/Phase 2)

Neoplasms (Phase 2)

Osteosarcoma (Phase 1/Phase 2)

Ovarian Neoplasms (Phase 2)

Pancreatic Neoplasms (Phase 1)

Small Cell Lung Carcinoma (Phase 1/Phase 2)

Triple Negative Breast Neoplasms (Phase 1/Phase 2)

Uterine Neoplasms (Phase 2)

Overview

Highest Phase: Phase 2
# of Trials: 11
# of Trial Organizations: 8

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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