maralixibat (LIVMARLI) Report issue

Small molecule Orphan Drug FDA Approved FDA Breakthrough Therapy FDA Priority Review FDA
AACT

Active Ingredient History

NOW
  • Now

Chemistry

  • SMILES: CCCCC1(CCCC)CS(=O)(=O)c2ccc(N(C)C)cc2[C@@H](c2ccc(OCc3ccc(C[N+]45CCN(CC4)CC5)cc3)cc2)[C@H]1O
  • InChIKey: STPKWKPURVSAJF-LJEWAXOPSA-N
  • Mol. Mass: 674.97
  • ALogP: 6.62
  • ChEMBL Molecules:
    maralixibat  
    maralixibat chloride  
More Chemistry

Pharmacology

Alternative names

lum001 | mrx-801

Organizations (8)

Research & Development (8)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (9)

Approved Indications (2)


 

Alagille Syndrome (approved 2021)

Pruritus (approved 2021)

Experimental Indications - Clinical Trial Phases 1-4 (8)


 

Alagille Syndrome (Phase 3)

Biliary Atresia (Phase 2)

Cholangitis (Phase 2)

Cholestasis (Phase 3)

Healthy Volunteers (Phase 1)

Ischemic Stroke (Phase 1/Phase 2)

Liver Cirrhosis, Biliary (Phase 2)

Liver Diseases (Phase 2)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 20
  • # of Trial Organizations: 8

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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