Cetalkonium Report issue

Small molecule Experimental

Active Ingredient History

NOW
  • Now
Cetalkonium chloride is a cationic quaternary ammonium surfactant, which is used for the treatment of mouth ulcers and sores (Bonjela trade name). It is also serves as an excipient for the purpose of long-term stabilization of ciclosporin ocular formulation, used in patients with dry eye syndrom (Ikervis trade name). The antibacterial properties of cetalkonium can be explained by its detergent character. Once applied, cetalkonium blocks the survival of biofilm forming bacterias.   NCATS

Chemistry

  • SMILES: CCCCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1
  • InChIKey: QDYLMAYUEZBUFO-UHFFFAOYSA-N
  • Mol. Mass: 360.6394
  • ALogP: 7.74
  • ChEMBL Molecule:
    cetalkonium  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Organizations (1)

Research & Development (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (5)

Approved Indications (3)


 

Dry Eye Syndromes (approved 2015)

Herpes Labialis

Oral Ulcer

Experimental Indications - Clinical Trial Phases 1-4 (2)


 

Drug-Related Side Effects and Adverse Reactions (Phase 2)

Mucositis (Phase 2)

Overview

  • Highest Phase: Phase 2
  • # of Trials: 3
  • # of Trial Organizations: 1

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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