tyramine Report issue

Small molecule Experimental
AACT DrugBank Drug Central PubChem

Active Ingredient History

NOW
  • Now
Tyramine, also known under several other names, is a naturally occurring trace amine derived from the amino acid tyrosine. Tyramine acts as a catecholamine releasing agent. Notably, it is unable to cross the blood-brain barrier, resulting in only non-psychoactive peripheral sympathomimetic effects following ingestion. A hypertensive crisis can result, however, from ingestion of tyramine-rich foods in conjunction with the use of monoamine oxidase inhibitors (MAOIs).   Wikipedia

Chemistry

More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Missing data
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: Missing data

Alternative names

2-(p-hydroxyphenyl)ethylamine | p-hydroxyphenethylamine | tyramine | tyramine hcl | tyramine hydrochloride | tyrosamine

Organizations (5)

Research & Development (5)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (6)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (6)


 

Autonomic Nervous System Diseases (Phase 1)

Dopamine beta-Hydroxylase (Phase 1)

Healthy Volunteers (Phase 1)

Hypotension, Orthostatic (Phase 1)

Orthostatic Intolerance (Phase 1)

Parkinson Disease (Phase 3)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 5
  • # of Trial Organizations: 5

Trials by Phase

Trial Phase Start Date Organizations Indications

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