tafamidis (Vyndaqel) Report issue

Small molecule Orphan Drug FDA Approved FDA First in Class Fast Track FDA Priority Review FDA

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Chemistry

Mol. Mass

308.12

ALogP

4.5

Rule of 5

Yes

Rule of 3

No
Details
  • SMILES: O=C(O)c1ccc2nc(-c3cc(Cl)cc(Cl)c3)oc2c1
  • InChIKey: TXEIIPDJKFWEEC-UHFFFAOYSA-N
    InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)
  • Chirality: Achiral Molecule
  • Inorganic: No
  • Polymer: No

Sources

CHEMBL2103837   ChEMBL
tafamidis *

CHEMBL2105675   ChEMBL
tafamidis meglumine

CHEMBL3545216   ChEMBL
fx-005

8FG9H9D31J   NCATS
tafamidis *

Tafamidis   Wikipedia

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