Active Ingredient History
Gossypol is a substance that is found in the cotton plant. It is removed from the seeds and used for medicine. Gossypol is effective as a nonhormonal male contraceptive; however, it has been documented to have irreversible effects on male fertility. Gossypol is reported to exhibit antioxidant, anticancer, antivirus, antiparasitic, and antimicrobial properties and lower plasma cholesterol. Nausea, emesis, anorexia, diarrhea, altered taste sensation, small intestine obstruction, and fatigue have been recorded in clinical trials as adverse reactions. Large amounts of gossypol can decrease potassium levels in the body. Low potassium levels can increase the side effects of digoxin. NCATS
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Adrenocortical Carcinoma (Phase 2)
Carcinoma, Non-Small-Cell Lung (Phase 3)
Esophageal Neoplasms (Phase 1/Phase 2)
Glioblastoma (Phase 2)
Laryngeal Neoplasms (Phase 2)
Leukemia, Lymphocytic, Chronic, B-Cell (Phase 2)
Lung Neoplasms (Phase 2)
Lymphoma, Follicular (Phase 2)
Lymphoma, Large B-Cell, Diffuse (Phase 2)
Lymphoma, Mantle-Cell (Phase 2)
Pregnancy (Phase 3)
Prostatic Neoplasms (Phase 2)
Small Cell Lung Carcinoma (Phase 1/Phase 2)
Squamous Cell Carcinoma of Head and Neck (Phase 2)
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