silver sulfadiazine (silvadene) Report issue

Small molecule Approved FDA Priority Review FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA PubChem repoDB

Active Ingredient History

NOW
  • Now
Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. Tentative evidence has found other antibiotics to be more effective, and therefore it is no longer generally recommended for second-degree (partial-thickness) burns, but is still widely used to protect third-degree (full-thickness) burns.   Wikipedia

Chemistry

  • SMILES: [Ag+].NC1=CC=C(C=C1)S(=O)(=O)[N-]C2=NC=CC=N2
  • InChIKey: UEJSSZHHYBHCEL-UHFFFAOYSA-N
  • Mol. Mass: 357.137
  • ALogP: 0.86
  • ChEMBL Molecules:
    sulfadiazine, silver  
    sulfadiazine  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Topical
  • Pro Drug: No

Drug Pricing (per unit)

United States

$0.0076 - $0.9300

Australia

$7.3421
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Alternative names

flamazine | silvadene | silver sulfadiazinate | silver sulfadiazine | silver sulphadiazine

Organizations (28)

Research & Development (24)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (4)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (5)

Approved Indications (1)


 

Burns (approved 1973)

Experimental Indications - Clinical Trial Phases 1-4 (5)


 

Breast Neoplasms (Phase 2)

Burns (Phase 4)

Head and Neck Neoplasms (Phase 2)

Tibial Fractures (Phase 3)

Wound Infection (Phase 1/Phase 2)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 22
  • # of Trial Organizations: 24

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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