novobiocin (albamycin) Report issue

Small molecule Approved FDA
ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Novobiocin, also known as albamycin, is an aminocoumarin antibiotic that is produced by the actinomycete Streptomyces niveus, which has recently been identified as a subjective synonym for S. spheroides a member of the class Actinomycetia. Other aminocoumarin antibiotics include clorobiocin and coumermycin A1. Novobiocin was first reported in the mid-1950s.   Wikipedia

Chemistry

  • SMILES: CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C
  • InChIKey: YJQPYGGHQPGBLI-KGSXXDOSSA-N
  • Mol. Mass: 612.63
  • ALogP: 3.63
  • ChEMBL Molecules:
    novobiocin  
    novobiocin sodium  
    novobiocin calcium  
More Chemistry

Pharmacology

Alternative names

albamycin | albamycin t | cardelmycin | cathomycin | inamycin | n-{7-[(3-o-carbamoyl-6-deoxy-5-methyl-4-o-methyl-beta-d-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2h-chromen-3-yl}-4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamide | novobiocin | novobiocina | novobiocin calcium | novobiocine | novobiocin sodium | novobiocin sodium salt | novobiocinum | spheromycin | streptonivicin

Organizations (2)

Research & Development (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (5)

Approved Indications (2)


 

Mastitis (approved 1983)

Staphylococcal Infections (approved 1964)

Experimental Indications - Clinical Trial Phases 1-4 (3)


 

Breast Neoplasms (Phase 1)

Carcinoma, Non-Small-Cell Lung (Phase 2)

Psoriasis ()

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