phylloquinone Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central PubChem repoDB

Active Ingredient History

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  • Now
Phytomenadione, also known as vitamin K1 or phylloquinone, is a vitamin found in food and used as a dietary supplement. It is on the World Health Organization's List of Essential Medicines.   Wikipedia

Chemistry

  • SMILES: CC1=C(C/C=C(\C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C(=O)c2ccccc2C1=O
  • InChIKey: MBWXNTAXLNYFJB-NKFFZRIASA-N
  • Mol. Mass: 450.71
  • ALogP: 9.16
  • ChEMBL Molecule:
    phytonadione  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Oral, Parenteral
  • Pro Drug: No

Alternative names

2-methyl-3-phytyl-1,4-naphthochinon | 2-methyl-3-phytyl-1,4-naphthoquinone | phyllochinonum | phylloquinone | phythyl-menadion | phytomenadione | phytomenadionum | phytonadionum | trans-phylloquinone | vitamin k

Organizations (14)

Research & Development (14)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (9)

Approved Indications (1)


 

Blood Coagulation Disorders

Experimental Indications - Clinical Trial Phases 1-4 (8)


 

Calciphylaxis (Phase 3)

Cerebellar Diseases (Early Phase 1)

Dietary Supplements ()

Glioblastoma (Phase 2)

Kidney Failure, Chronic (Phase 2/Phase 3)

Osteoporosis (Phase 3)

Osteoporosis, Postmenopausal (Phase 2/Phase 3)

Vascular Calcification (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 9
  • # of Trial Organizations: 14

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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