tolnaftate Report issue

Small molecule Experimental
ChEMBL DrugBank Drug Central KEGG MeSH PubChem repoDB

Active Ingredient History

Tolnaftate is a thiocarbamate derivative used as an over-the-counter anti-fungal agent for treatment of athlete's foot and ringworm. Tolnaftate acts by inhibition of ergosterol biosynthesis pathway in fungal cells.   NCATS

Chemistry

  • SMILES: CN(C(=S)OC1=CC=C2C=CC=CC2=C1)C3=CC=CC(C)=C3
  • InChIKey: FUSNMLFNXJSCDI-UHFFFAOYSA-N
  • Mol. Mass: 307.409
  • ALogP: 0.94
  • ChEMBL Molecules:
    nystatin  
    tolnaftate  
More Chemistry

Pharmacology

Drug Pricing (per unit)

United States

$0.0336 - $0.1603

Australia

$5.8458
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Alternative names

2-naphthyl n-methyl-n-(3-tolyl)thionocarbamate | aftate | methyl (3-methylphenyl)carbamothioic acid o-2-naphthalenyl ester | m,n-dimethylthiocarbanilic acid o-2-naphthyl ester | n-methyl-n-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide | o-2-naphthyl m,n-dimethylthiocarbanilate | separin | tinactin | tinaderm | tinaderm m | tolnaftate | tolnaftato | tolnaftatum | tolnaphthate | tolsanil | tonoftal

Indications (3)

Approved Indications (3)


 

Tinea

Tinea Pedis

Tinea Versicolor

Experimental Indications - Clinical Trial Phases 1-4 (0)

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