lindane (kwell) Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Lindane is an isomer of hexachlorocyclohexane that has been used both as an agricultural insecticide and as a pharmaceutical. As a shampoo, lindane is used for treamtment lice infestation. Lindane lotion is used for treatment of scabies. Due to toxicities, associated with lindane, it is used only in patients who cannot tolerate or have failed first-line treatment with safer medication. Lindane exerts its parasiticidal action by being directly absorbed into the parasites and their ova, where it interferes with GABA neurotransmitter function by interacting with the GABAA channel complex at the picrotoxin binding site.   NCATS

Chemistry

More Chemistry

Pharmacology

Alternative names

1,2,3,4,5,6-hexachlorocyclohexane | (1alpha,2alpha,3beta,4alpha,5alpha,6beta)-1,2,3,4,5,6-hexachlorocyclohexane | (1r,2c,3t,4c,5c,6t)-1,2,3,4,5,6-hexachlorocyclohexane | benzene hexachloride | benzene hexachloride, gamma | esoderm | gamene | gamma-1,2,3,4,5,6-hexachlorocyclohexane | gamma benzene hcl | gamma benzene hexachloride | gamma-benzene hexachloride | gamma-bhc | gamma-hch | gamma-hexachlorocyclohexane | gamma-hexachlorzyklohexan | gamma-lindane | gammallin | gammaxene | gammexane | gexane | hexachloran | hexachlorane | hexachlorocyclohexane | hexicide | kwell | kwells | kwells kids | lindan | lindane | lorexane | lorexane no 3 | quellada | quellada-m | scabene | γ-hexachlorocyclohexane | γ-hexachlorzyklohexan | γ-lindane

Organizations (8)

Research & Development (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (6)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (4)

Approved Indications (2)


 

Lice Infestations (approved 1975)

Scabies (approved 1974)

Experimental Indications - Clinical Trial Phases 1-4 (2)


 

Pediculus (Phase 2)

Pharmacology (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 2
  • # of Trial Organizations: 2

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue