cefapirin (Cefadyl) Report issue

Small molecule Approved FDA
ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Cephapirin is a first-generation cephalosporin. Cephapirin has been indicated for the treatment of infections when caused by susceptible strains in respiratory, genitourinary, gastrointestinal, skin and soft tissue, bone and joint infections, septicemia; treatment of susceptible gram-positive bacilli and cocci (never enterococcus); some gram-negative bacilli including E. coli, Proteus, and Klebsiella may be susceptible. Cephapirin is used in veterinary as an intra-uterine antibiotic infusion for the treatment of subacute and chronic endometritis in cows and repeat breeders.   NCATS

Chemistry

  • SMILES: CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)CSc3ccncc3)[C@H]2SC1
  • InChIKey: UQLLWWBDSUHNEB-CZUORRHYSA-N
  • Mol. Mass: 423.47
  • ALogP: 0.48
  • ChEMBL Molecules:
    cephapirin  
    cephapirin sodium  
More Chemistry

Pharmacology

Alternative names

(6r,7r)-3-(acetoxymethyl)-8-oxo-7-{[(pyridin-4-ylsulfanyl)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | bl-p-1322 | cefadyl | cefapirin | cefapirina | cefapirine | cefapirin sodium | cefapirinum | cefaprin | cephapirin | cephapirine | cephapirin sodium | cephaprin | cepr | sodium cefapirin

Organizations (6)

Research & Development (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (5)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (2)

Approved Indications (1)


 

Bacterial Infections (approved 1974)

Experimental Indications - Clinical Trial Phases 1-4 (1)


 

Cystitis (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 1
  • # of Trial Organizations: 1

Trials by Phase

Trial Phase Start Date Organizations Indications

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