Active Ingredient History

  • Now
Tripelennamine (sold as Pyribenzamine by Novartis) is a drug that is used as an antipruritic and first-generation antihistamine. Histamine acting on H1-receptors produces vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Tripelennamine can be used in the treatment of asthma, hay fever, rhinitis, and urticaria, but is now less common as newer antihistamines have replaced it.   NCATS

More Chemistry
  • Mechanisms of Action: Missing data
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Discontinued
  • Delivery Methods: Oral
  • Pro Drug: No
pbz | pbz-sr | pyribenzamin | pyribenzamine | pyrinamine base | tripelenamine | tripelennamin | tripelennamina | tripelennamine | tripélennamine | tripelennamine chloride | tripelennamine citrate | tripelennamine hcl | tripelennamine hydrochloride | tripelennaminum


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