dinoprost Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

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Dinoprost is the synthetic or partially synthetic, naturally-occurring prostaglandin F2 alpha (trade mark Prostin F2 alpha). Dinoprost has been used for therapeutic termination of pregnancy. Although the exact mode of action in pregnancy termination in humans is not fully defined, when Prostin F2 alpha is administered by the intrauterine route it initiates rhythmical uterine contractions which, if continued for a sufficient time, are capable of expelling the contents of the uterus. Sensitivity of the pregnant uterus to prostaglandins is lower during early and mid-pregnancy than at term.   NCATS

Chemistry

More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Discontinued
  • Delivery Methods: Parenteral
  • Pro Drug: No

Alternative names

dinoprost | dinoprost trometamol | dinoprost tromethamine | enzaprost | pge2 | pgf2-alpha tham | pgf2alpha tham | pgf2alpha-tham | prepidil | prostaglandin e2 | prostaglandin f2 | prostaglandin f 2 alpha | prostaglandin f2 alpha | prostaglandin f2-alpha tham | prostaglandin f2alpha tham | prostaglandin f2a tromethamine | prostin f2 alpha | u-14583 | u-14583e

Organizations (12)

Research & Development (12)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (6)

Approved Indications (1)


 

Obstetric Labor Complications

Experimental Indications - Clinical Trial Phases 1-4 (5)


 

Cervical Ripening (Phase 3)

Fetal Membranes, Premature Rupture (Phase 4)

Infant, Premature (Phase 4)

Labor, Induced (Phase 3)

Uterus (Phase 2)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 11
  • # of Trial Organizations: 12

Trials by Phase

Trial Phase Start Date Organizations Indications

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