calcitonin, human (cibacalcin) Report issue

Small molecule Approved FDA Priority Review FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA PubChem

Active Ingredient History

NOW
  • Now
Calcitonin is a 32 amino acid peptide hormone secreted by parafollicular cells (also known as C cells) of the thyroid (or endostyle) in humans and other chordates in the ultimopharyngeal body. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH).   Wikipedia

Chemistry

  • SMILES: CNC(Cc1ccccc1)C(=O)C(C)C2CC(=O)NCCCC(CC(=C)C(Cc3c[nH]cn3)C(C)C(=O)C(Cc4ccccc4)CC(=O)C(CCCCN)C(C)C2=C)C(=O)C
  • InChIKey: DFBUKAGMZUKJGY-UHFFFAOYSA-N
  • Mol. Mass: 834.16
  • ALogP: 7.63
  • ChEMBL Molecules:
    calcitonin human  
    calcitonin  
    calcitonin human  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Discontinued
  • Delivery Methods: Parenteral
  • Pro Drug: No

Alternative names

calcitonin human | calcitonin (human) | calcitonin, human | calcitonin (human synthetic) | calcitonin, human synthetic | cibacalcin | hc-58 | human calcitonin

Organizations (3)

Research & Development (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (2)

Approved Indications (1)


 

Paget Disease, Extramammary (approved 1986)

Experimental Indications - Clinical Trial Phases 1-4 (1)


 

Hemiplegia (Phase 2)

Overview

  • Highest Phase: Phase 2
  • # of Trials: 1
  • # of Trial Organizations: 1

Trials by Phase

Trial Phase Start Date Organizations Indications

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