sulfaphenazole (sulfabid) Report issue

Small molecule Approved FDA
ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Sulfaphenazole is an oral antibiotic, which was used for the treatment of bacterial infections under the name Sulfabid. The drug was found to block folate synthesis in bacterias by inhibiting the enzyme dihydropteroate synthase. Sulfaphenazole is also known to inhibit CYP2C9 with high potency and specificity. Sulfabid is no longer marketed in the USA.   NCATS

Chemistry

  • SMILES: NC1=CC=C(C=C1)S(=O)(=O)NC2=CC=NN2C3=CC=CC=C3
  • InChIKey: QWCJHSGMANYXCW-UHFFFAOYSA-N
  • Mol. Mass: 314.362
  • ALogP: 2.26
  • ChEMBL Molecule:
    sulfaphenazole  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Discontinued
  • Delivery Methods: Oral
  • Pro Drug: No

Alternative names

1-phenyl-5-sulfanilamidopyrazole | 3-(p-aminobenzenesulfonamido)-2-phenylpyrazole | 5-sulfanilamido-1-phenylpyrazole | n(1)-(1-phenylpyrazol-5-yl)sulfanilamide | n'-(1-phenylpyrazol-5-yl)sulfanilamide | orisulf | sulfabid | sulfafenazol | sulfafenazolo | sulfaphenazol | sulfaphenazole | sulfaphenazolum | sulfaphenazon | sulfaphenylpyrazole | sulphaphenazole

Organizations (2)

Research & Development (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (1)

Approved Indications (1)


 

Bacterial Infections (approved 1974)

Experimental Indications - Clinical Trial Phases 1-4 (0)

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