meclocycline (declomycin) Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Meclocycline is a tetracycline antibiotic. It is used topically for skin infections treatment. Tetracyclines are broad-spectrum bacteriostatic agents and act by inhibiting protein synthesis by blocking the binding of aminoacyl tRNA (transfer RNA) to the mRNA (messenger RNA) ribosome complex. Meclocycline might increase sensitivity to light when it is used with Aminolevulinic acid.   NCATS

Chemistry

  • SMILES: CN(C)[C@H]1[C@@H]2[C@@H](O)[C@@H]3C(=C)C4=C(Cl)C=CC(O)=C4C(=O)C3=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O
  • InChIKey: GGQJXCQBBONZFX-IWVLMIASSA-N
  • Mol. Mass: 476.864
  • ALogP: 0.22
  • ChEMBL Molecules:
    meclocycline  
    meclocycline sulfosalicylate  
More Chemistry

Pharmacology

Alternative names

7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacene carboxamide | gs 2989 | meclan | meclocil | meclocycline | meclocycline monohydrochloride, (4s-(4alpha,4aalpha,5alpha,5aalpha,12aalpha))-isomer | meclocycline sulfosalicylate | mecloderm | meclosorb | quoderm | samil | traumatociclina

Organizations (3)

Research & Development (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (2)

Approved Indications (1)


 

Acne Vulgaris (approved 1981)

Experimental Indications - Clinical Trial Phases 1-4 (1)


 

Stomatitis (Phase 2)

Overview

  • Highest Phase: Phase 2
  • # of Trials: 1
  • # of Trial Organizations: 1

Trials by Phase

Trial Phase Start Date Organizations Indications

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