hexetidine (hexoral) Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Hexetidine is very safe oral antiseptic with broad antibacterial and antifungal activity in vivo and in vitro. It has local-anesthetics, astringent and deodorant activity. Also, it has very strong antiplac effects. Resistention of microorganisms on hexetidine is short and transient. These characteristics give important therapeutic role in treatment of oral infections. In the UK, hexetidine is the active ingredient in the medicated mouthwash branded Oraldene. Oraldene contains 0.1 g/100 ml of hexetidine. In Germany, hexetidine is used for vaginal antisepsis.   NCATS

Chemistry

  • SMILES: CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1
  • InChIKey: DTOUUUZOYKYHEP-UHFFFAOYSA-N
  • Mol. Mass: 339.6021
  • ALogP: 4.71
  • ChEMBL Molecule:
    hexetidine  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

esetidina | glypesin | hexetedine | hexetidine | hexétidine | hexopyrimidine | hexoral | oraldene | sterisil

Organizations (1)

Research & Development (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (5)

Approved Indications (3)


 

Candidiasis, Oral

Gingivitis

Ulcer

Experimental Indications - Clinical Trial Phases 1-4 (2)


 

Disinfectants ()

Stomatitis (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 1
  • # of Trial Organizations: 1

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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