Diseases [C] » Pathological Conditions, Signs and Symptoms [C23] » Pathologic Processes » Ochronosis
Description
The yellowish discoloration of connective tissue due to deposition of HOMOGENTISIC ACID (a brown-black pigment). This is due to defects in the metabolism of PHENYLALANINE and TYROSINE. Ochronosis occurs in ALKAPTONURIA, but has also been associated with exposure to certain chemicals (e.g., PHENOL, trinitrophenol, BENZENE DERIVATIVES). MeSH
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Organization Involved with Phase 3 Indications (3)
Organization Involved with Phase 2 Indications (1)
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