killed oral cholera vaccine Report issue

Vaccine Experimental
AACT

Active Ingredient History

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A cholera vaccine is a vaccine that is effective at reducing the risk of contracting cholera. The recommended cholera vaccines are administered orally to elicit local immune response in the gut where the intestinal cells produce antibodies against the cholera microbe. This immune response was poorly achieved with the injectable vaccines that were used until the 1970s. The first effective oral cholera vaccine was Dukoral, developed in Sweden in the 1980s. For the first six months after vaccination it provides about 85 percent protection, which decreases to approximately 60 percent during the first two years. When enough of the population is immunized, it may protect those who have not been immunized thereby increasing the total protective impact to more than 90 percent.   Wikipedia

Chemistry

More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Missing data
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: Missing data

Alternative names

bivalent killed oral cholera vaccine | bivalent killed whole cell oral cholera vaccine | dukoral | euvichol | killed oral cholera vaccine | killed whole cell oral cholera vaccine | oral cholera vaccine | whole cell killed cholera vaccine

Organizations (36)

Research & Development (36)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (16)

Approved Indications (1)


 

Cholera

Experimental Indications - Clinical Trial Phases 1-4 (16)


 

Cholera (Phase 4)

Cholera Vaccines (Phase 2)

Colitis, Ulcerative (Phase 2)

Diarrhea (Phase 3)

Drug-Related Side Effects and Adverse Reactions (Phase 2)

Immunity (Phase 4)

Infections (Phase 1)

Kidney Transplantation (Phase 4)

Measles (Phase 3)

Primary Prevention (Phase 3)

Rubella (Phase 3)

Typhoid Fever (Phase 4)

Vaccine-Preventable Diseases (Phase 4)

Vaccines (Phase 3)

Vibrio cholerae (Phase 4)

Vibrio Infections (Phase 3)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 27
  • # of Trial Organizations: 36

Trials by Phase

Trial Phase Start Date Organizations Indications

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