autologous culture chondrocytes (Carticel) Report issue

Cell therapy Approved FDA
AACT DrugBank

Active Ingredient History

NOW
  • Now
Chondrocytes are the only cells found in healthy cartilage. They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans. Although the word chondroblast is commonly used to describe an immature chondrocyte, the term is imprecise, since the progenitor of chondrocytes can differentiate into various cell types, including osteoblasts.   Wikipedia

Chemistry

More Chemistry

Pharmacology

  • Mechanisms of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

autologous chondrocyte | autologous chondrocytes | autologous cultured chondrocytes | carticel sm service | chondrocytes | spheroids of human autologous matrix-associated chondrocytes

Organizations (39)

Research & Development (39)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (1)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (18)

Approved Indications (1)


 

Cartilage Diseases (approved 1997)

Experimental Indications - Clinical Trial Phases 1-4 (18)


 

Bone Cysts (Phase 1)

Cartilage (Phase 1)

Cartilage, Articular (Phase 4)

Cartilage Diseases (Phase 3)

Congenital Microtia (Early Phase 1)

Fractures, Bone (Phase 1)

Intervertebral Disc Degeneration (Phase 2)

Intervertebral Disc Displacement (Phase 1/Phase 2)

Joint Diseases (Phase 1/Phase 2)

Liver Cirrhosis (Phase 1)

Mandibular Condyle (Phase 2)

Nasal Septal Perforation (Phase 1)

Osteoarthritis, Hip (Phase 1)

Osteochondritis (Phase 3)

Osteochondritis Dissecans (Phase 3)

Temporomandibular Joint Disorders (Phase 1)

Traumatology (Phase 3)

Vesico-Ureteral Reflux (Phase 3)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 30
  • # of Trial Organizations: 39

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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