API | apricitabine

apricitabine Report issue

Small molecule Experimental

AACT DrugBank MeSH PubChem

Active Ingredient History

NOW

Apricitabine is an experimental nucleoside reverse transcriptase inhibitor (NRTI) against HIV. It is structurally related to lamivudine and emtricitabine, and, like these, is an analogue of cytidine. ^Wikipedia

Chemistry

SMILES: Nc1ccn([C@H]2CO[C@@H](CO)S2)c(=O)n1
InChIKey: RYMCFYKJDVMSIR-RNFRBKRXSA-N
Mol. Mass: 229.26
ALogP: -0.59 Partition coefficient
ChEMBL Molecule:
apricitabine

More Chemistry

Pharmacology

Mechanisms of Action:
- Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) ^UniProt
- Reverse transcriptase (Human immunodeficiency virus 2) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: Yes

apricitabine | avx754 | avx-754 | bch10619 | bch 10619 | bch-10619 | spd754

Organizations (2)

Research & Development (2)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (1)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (1)

HIV Infections (Phase 3)

Overview

Highest Phase: Phase 3
# of Trials: 6
# of Trial Organizations: 2

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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