vinflunine Report issue

Small molecule Experimental
AACT ChEMBL Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Vinflunine is a novel fluorinated vinca alkaloid derivative undergoing research for the treatment of bladder cancer. It was originally discovered by the team of the Professor Jean-Claude Jacquesy, developed by Laboratoires Pierre Fabre and was licensed to Bristol-Myers Squibb for development in certain countries, including the United States.   Wikipedia

Chemistry

  • SMILES: CC[C@]12C=CCN3CC[C@@]4(c5cc([C@@]6(C(=O)OC)C[C@@H]7C[C@@H](C(C)(F)F)CN(Cc8c6[nH]c6ccccc86)C7)c(OC)cc5N(C)[C@H]4[C@@](O)(C(=O)OC)[C@@H]1OC(C)=O)[C@@H]32
  • InChIKey: NMDYYWFGPIMTKO-KLCPSUAYSA-N
  • Mol. Mass: 816.94
  • ALogP: 5.08
  • ChEMBL Molecules:
    vinflunine  
    None  
More Chemistry

Pharmacology

Alternative names

javlor | vinflunine | vinflunine ditartrate

Organizations (26)

Research & Development (26)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (15)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (15)


 

Breast Neoplasms (Phase 3)

Carcinoma, Non-Small-Cell Lung (Phase 2)

Carcinoma, Small Cell (Phase 2)

Carcinoma, Transitional Cell (Phase 3)

Kidney Neoplasms (Phase 2)

Lung Neoplasms (Phase 2)

Neoplasm Metastasis (Phase 3)

Neoplasms ()

Penile Neoplasms (Phase 2)

Prostatic Neoplasms (Phase 2)

Squamous Cell Carcinoma of Head and Neck (Phase 3)

Stomach Neoplasms (Phase 2/Phase 3)

Ureteral Neoplasms (Phase 3)

Urethral Neoplasms (Phase 2)

Urinary Bladder Neoplasms (Phase 3)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 32
  • # of Trial Organizations: 26

Trials by Phase

Trial Phase Start Date Organizations Indications

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