API | tarloxotinib

tarloxotinib Report issue

Small molecule Experimental

AACT PubChem

Active Ingredient History

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Chemistry

SMILES: Cn1cnc([N+](=O)[O-])c1C[N+](C)(C)C/C=C/C(=O)Nc1cc2c(Nc3ccc(Cl)c(Br)c3)ncnc2cn1
InChIKey: MUJMYVFVAWFUJL-SNAWJCMRSA-O
Mol. Mass: 601.87
ALogP: 4.6 Partition coefficient
ChEMBL Molecules:

tarloxotinib

tarloxotinib bromide

More Chemistry

Pharmacology

Mechanisms of Action:
- Epidermal growth factor receptor (Homo sapiens) ^UniProt
- Potassium voltage-gated channel subfamily H member 2 (Homo sapiens) ^UniProt
- Receptor tyrosine-protein kinase erbB-2 (Homo sapiens) ^UniProt
- Receptor tyrosine-protein kinase erbB-4 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: Yes

pr610 | tarloxotinib

Organizations (6)

Research & Development (6)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (6)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (6)

Breast Neoplasms (Phase 2)

Carcinoma, Non-Small-Cell Lung (Phase 2)

ErbB Receptors (Phase 2)

Mutation (Phase 2)

Neoplasms (Phase 1/Phase 2)

Squamous Cell Carcinoma of Head and Neck (Phase 2)

Overview

Highest Phase: Phase 2
# of Trials: 5
# of Trial Organizations: 6

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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