Active Ingredient History
Rocuronium (brand names Zemuron, Esmeron) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation, most commonly required for surgery or mechanical ventilation. Rocuronium bromide is a nondepolarizing neuromuscular blocking agent with a rapid to intermediate onset depending on dose and intermediate duration. It acts by competing for cholinergic receptors at the motor end-plate. This action is antagonized by acetylcholinesterase inhibitors, such as neostigmine and edrophonium. Most common adverse reactions are transient hypotension and hypertension. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
---|
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
---|
Somatoform Disorders (approved 1994)
Acute-On-Chronic Liver Failure (Phase 4)
Airway Management (Phase 4)
Analgesia (Phase 4)
Analgesics, Opioid (Phase 4)
Anesthesia (Phase 4)
Anesthesia and Analgesia (Phase 4)
Anesthesia, General (Phase 4)
Anesthesia, Local (Phase 3)
Anesthesia, Spinal (Phase 4)
Appendicitis (Phase 3)
Arthritis (Phase 4)
Arthroplasty, Replacement, Hip (Phase 4)
Back Pain (Phase 3)
Bariatric Surgery (Phase 4)
Carcinoid Tumor (Phase 2)
Carcinoma, Renal Cell (Phase 2)
Cesarean Section (Phase 4)
Cholecystectomy, Laparoscopic (Phase 4)
Cholecystitis (Phase 4)
Colorectal Surgery (Phase 4)
Coma (Phase 4)
Coronary Artery Disease (Phase 4)
Delayed Emergence from Anesthesia (Phase 4)
Delirium (Early Phase 1)
Diaphragm (Phase 3)
Endometriosis (Phase 4)
Epigenomics (Phase 4)
Esophageal and Gastric Varices (Phase 4)
Esophageal Neoplasms (Phase 4)
Extracorporeal Membrane Oxygenation (Phase 4)
Fractures, Bone (Early Phase 1)
Gallbladder Diseases (Phase 4)
Gastric Bypass (Phase 4)
Gastrointestinal Neoplasms (Phase 4)
General Surgery (Phase 4)
Glioblastoma (Phase 2)
Gynecology (Phase 4)
Heart Arrest (Phase 2)
Heart Defects, Congenital (Phase 4)
Heart Diseases (Phase 3)
Hemodynamics (Phase 4)
Hernia, Inguinal (Phase 4)
High-Frequency Jet Ventilation (Phase 1)
Hip Fractures (Phase 4)
Hypothermia (Phase 3)
Hypoxia (Phase 4)
Hysterectomy (Phase 4)
Immune System Diseases (Phase 4)
Inflammation (Phase 4)
Inhalation (Phase 4)
Intensive Care Units (Phase 4)
Intestinal Diseases (Phase 4)
Intestinal Pseudo-Obstruction (Phase 4)
Intraocular Pressure (Phase 4)
Intraoperative Awareness (Phase 4)
Intubation (Phase 4)
Intubation, Intratracheal (Phase 4)
Kidney Diseases (Phase 4)
Kidney Failure, Chronic (Phase 2)
Kidney Transplantation (Phase 4)
Laparoscopy (Phase 4)
Laryngeal Masks (Phase 4)
Laryngoscopy (Phase 4)
Leiomyoma (Phase 4)
Lung Diseases (Phase 4)
Lung Neoplasms (Phase 2/Phase 3)
Multiple Myeloma (Phase 2)
Muscle Fatigue (Phase 3)
Muscle Relaxants, Central (Phase 4)
Muscle Relaxation (Phase 4)
Muscle Weakness (Phase 3)
Myalgia (Phase 3)
Myoclonus (Phase 4)
Nausea (Phase 4)
Neoplasm Metastasis (Phase 4)
Neoplasms (Phase 4)
Nerve Block (Phase 3)
Neuromuscular Blockade (Phase 4)
Obesity (Phase 4)
Obesity, Morbid (Phase 4)
Organophosphate Poisoning (Phase 2/Phase 3)
Osteoarthritis (Phase 4)
Out-of-Hospital Cardiac Arrest (Phase 2)
Ovarian Neoplasms (Phase 2)
Pain (Phase 4)
Pain, Postoperative (Phase 4)
Pancreatic Neoplasms (Phase 3)
Pathology (Phase 4)
Pneumoperitoneum (Phase 4)
Postoperative Complications (Phase 4)
Pregnancy (Phase 4)
Prostatic Neoplasms (Phase 4)
Quality of Life (Phase 4)
Rapid Sequence Induction and Intubation (Phase 4)
Renal Insufficiency, Chronic (Phase 4)
Respiratory Distress Syndrome (Phase 4)
Respiratory Insufficiency (Phase 4)
Rotator Cuff Injuries (Phase 4)
Shock (Phase 4)
Spinal Diseases (Phase 4)
Spinal Fusion (Phase 3)
Spinal Stenosis (Early Phase 1)
Tracheostomy (Phase 4)
Traumatology (Phase 4)
Urinary Bladder Neoplasms (Phase 4)
Urologic Diseases (Phase 4)
Uterine Prolapse (Phase 4)
Vascular Diseases (Phase 4)
Vocal Cord Dysfunction (Phase 1)
Vomiting (Phase 4)
Trial | Phase | Start Date | Organizations | Indications |
---|
Feedback
Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).
Report issue