alisporivir Report issue

Small molecule Experimental
AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

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Alisporivir (INN), or Debio 025, DEB025, is a cyclophilin inhibitor. Its structure is reminiscent of, and synthesized from ciclosporin.   Wikipedia

Chemistry

  • SMILES: C/C=C/C[C@@H](C)[C@@H](O)[C@H]1C(=O)N[C@@H](CC)C(=O)N(C)[C@H](C)C(=O)N(CC)[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](C(C)C)C(=O)N1C
  • InChIKey: OLROWHGDTNFZBH-XEMWPYQTSA-N
  • Mol. Mass: 1216.66
  • ALogP: Missing data
  • ChEMBL Molecule:
    alisporivir  
More Chemistry

Pharmacology

Alternative names

alisporivir | deb025 | debio 025 | debio-025 | meala(3)etval(4)-cyclosporin | unil025 | unil 025 | unil-025

Organizations (6)

Research & Development (6)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (8)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (8)


 

Chronic Pain (Phase 2)

Hepacivirus (Phase 1)

Hepatic Insufficiency (Phase 1)

Hepatitis C (Phase 3)

Hepatitis C, Chronic (Phase 3)

Kidney Failure, Chronic (Phase 1)

Liver Diseases (Phase 2)

SARS-CoV-2 (Phase 2)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 15
  • # of Trial Organizations: 6

Trials by Phase

Trial Phase Start Date Organizations Indications

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