nitrendipine Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem repoDB

Active Ingredient History

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Nitrendipine is a dihydropyridine calcium channel blocker. It is used in the treatment of primary (essential) hypertension to decrease blood pressure and can reduce the cardiotoxicity of cocaine.   Wikipedia

Chemistry

  • SMILES: CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1
  • InChIKey: PVHUJELLJLJGLN-UHFFFAOYSA-N
  • Mol. Mass: 360.37
  • ALogP: 2.57
  • ChEMBL Molecule:
    nitrendipine  
More Chemistry

Pharmacology

Alternative names

1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester | bay e 5009 | bay-e-5009 | bayotensin | baypress | bylotensin | deiten | nidrel | nitrendipin | nitrendipine | nitrendipino | nitrendipinum | nitrepin

Organizations (6)

Research & Development (6)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (2)

Approved Indications (1)


 

Hypertension

Experimental Indications - Clinical Trial Phases 1-4 (2)


 

Hypertension (Phase 4)

Renal Insufficiency, Chronic (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 6
  • # of Trial Organizations: 6

Trials by Phase

Trial Phase Start Date Organizations Indications

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