Active Ingredient History
Botulinum toxin, or botulinum neurotoxin, is a highly potent neurotoxic protein produced by the bacterium Clostridium botulinum and related species. It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. The toxin causes the disease botulism. The toxin is also used commercially for medical and cosmetic purposes. Botulinum toxin is an acetylcholine release inhibitor and a neuromuscular blocking agent. Wikipedia
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Dystonia (approved 2000)
Acne Vulgaris (Phase 2)
Aging (Phase 4)
Alopecia (Phase 2/Phase 3)
Amyotrophic Lateral Sclerosis (Phase 2/Phase 3)
Anxiety (Phase 4)
Arm (Phase 3)
Arrhythmias, Cardiac (Phase 2)
Arthritis (Phase 4)
Atrial Fibrillation (Phase 2/Phase 3)
Atrial Flutter (Phase 2)
Atrophy (Phase 4)
Autonomic Dysreflexia (Phase 4)
Back Pain (Phase 4)
Blepharitis (Phase 4)
Blepharospasm (Phase 4)
Botulinum Toxins (Phase 4)
Botulinum Toxins, Type A (Phase 2)
Brachial Plexus Neuritis (Phase 4)
Brain Injuries (Phase 4)
Brain Injuries, Traumatic (Phase 3)
BRCA1 Protein (Phase 3)
Breast Diseases (Phase 4)
Breast Neoplasms (Phase 4)
Bruxism (Phase 4)
Burning Mouth Syndrome (Phase 2)
Carcinoma, Renal Cell (Phase 2)
Carpal Tunnel Syndrome (Phase 2)
Cerebral Palsy (Phase 4)
Cervix Uteri (Phase 2)
Child (Phase 3)
Chronic Disease (Phase 2)
Chronic Pain (Phase 4)
Cicatrix (Phase 4)
Cleft Lip (Phase 1/Phase 2)
Cleft Palate (Phase 1/Phase 2)
Clostridium Infections (Phase 4)
Cluster Headache (Phase 1/Phase 2)
Colostomy (Phase 2)
Constipation (Phase 4)
Contracture (Phase 2)
Coronary Artery Bypass (Phase 2)
Cystitis, Interstitial (Phase 4)
Darier Disease (Phase 1)
Defecation (Phase 2)
Dementia (Phase 2)
Depression (Phase 4)
Depressive Disorder, Major (Phase 2)
Dermatitis, Seborrheic (Phase 1)
Dermatology (Phase 4)
Diabetic Neuropathies (Phase 4)
Dry Eye Syndromes (Phase 1)
Dystonia (Phase 3)
Dystonic Disorders (Phase 4)
Elbow (Phase 1/Phase 2)
Endocardial Fibroelastosis (Phase 4)
Endometriosis (Phase 1/Phase 2)
Epidermolysis Bullosa Simplex (Phase 2)
Erectile Dysfunction (Phase 2/Phase 3)
Esophageal Diseases (Phase 2)
Esophageal Neoplasms (Phase 2)
Esotropia (Phase 4)
Essential Tremor (Phase 4)
Esthetics (Phase 4)
Exotropia (Phase 4)
Eyebrows (Phase 4)
Eye Diseases (Phase 2/Phase 3)
Eyelid Diseases (Phase 4)
Face (Phase 4)
Facial Asymmetry (Phase 4)
Facial Nerve Injuries (Phase 4)
Facial Pain (Phase 4)
Fasciitis, Plantar (Phase 2/Phase 3)
Fecal Incontinence (Phase 3)
Fibromyalgia (Phase 4)
Finger Injuries (Phase 4)
Fissure in Ano (Phase 4)
Foot (Phase 2)
Foot Deformities (Phase 4)
Friedreich Ataxia (Phase 1/Phase 2)
General Surgery (Phase 2)
Granuloma (Phase 2)
Granuloma, Laryngeal (Phase 2)
Graves Ophthalmopathy (Phase 4)
Hallux Valgus (Phase 4)
Headache (Phase 3)
Headache Disorders (Phase 1/Phase 2)
Healthy Volunteers (Phase 4)
Hemifacial Spasm (Phase 3)
Hemiplegia (Phase 3)
Hyperalgesia (Phase 3)
Hyperhidrosis (Phase 4)
Hypertrophy, Left Ventricular (Phase 1)
Lacrimal Apparatus Diseases (Phase 2)
Leg Length Inequality (Phase 4)
Low Back Pain (Phase 4)
Lower Extremity Deformities, Congenital (Phase 3)
Lower Urinary Tract Symptoms (Phase 2)
Masseter Muscle (Phase 2)
Meningomyelocele (Phase 4)
Migraine Disorders (Phase 4)
Motor Neuron Disease (Phase 2)
Multiple Sclerosis (Phase 4)
Multiple System Atrophy (Phase 4)
Muscle Spasticity (Phase 4)
Mutation (Phase 3)
Myocardial Ischemia (Phase 2)
Myofascial Pain Syndromes (Phase 4)
Myoma (Phase 2)
Nasal Polyps (Phase 2)
Nasolabial Fold (Phase 4)
Neck Pain (Phase 1)
Neoplasms (Phase 4)
Neoplasms by Site (Phase 4)
Nervous System Diseases (Phase 3)
Neuralgia (Phase 4)
Neuralgia, Postherpetic (Phase 4)
Neuroma (Phase 2)
Nose (Phase 1/Phase 2)
Obesity (Phase 2)
Obesity, Morbid (Phase 2)
Opioid-Related Disorders (Phase 2)
Osteoarthritis (Phase 2/Phase 3)
Osteoarthritis, Knee (Phase 4)
Pain (Phase 4)
Pain, Postoperative (Phase 3)
Paresis (Phase 2)
Parkinson Disease (Phase 4)
Parkinsonian Disorders (Phase 1)
Patellofemoral Pain Syndrome (Phase 3)
Pediatrics (Phase 3)
Pemphigus, Benign Familial (Phase 1)
Penile Induration (Phase 2)
Phobia, Social (Phase 4)
Placebos (Phase 3)
Polyneuropathies (Phase 4)
Post-Traumatic Headache (Phase 2)
Premature Ejaculation (Phase 2)
Prostatic Hyperplasia (Phase 3)
Prostatic Neoplasms (Phase 2/Phase 3)
Prostatitis (Phase 3)
Prostheses and Implants (Phase 2)
Pruritus (Phase 1/Phase 2)
Psoriasis (Phase 1)
Quality of Life (Phase 4)
Raynaud Disease (Phase 3)
Rectal Neoplasms (Phase 2)
Rectum (Phase 2/Phase 3)
Restless Legs Syndrome (Phase 2)
Rhinitis (Phase 2)
Rhinitis, Atrophic (Phase 1/Phase 2)
Rhytidoplasty (Phase 4)
Rotator Cuff Tear Arthropathy (Phase 2)
Scleroderma, Systemic (Phase 3)
Sclerosis (Phase 2)
Seminal Vesicles (Phase 3)
Sexual Dysfunction, Physiological (Phase 2/Phase 3)
Shoulder Pain (Phase 3)
Sialorrhea (Phase 3)
Skin Aging (Phase 4)
Skin Diseases (Phase 4)
Sleep Apnea Syndromes (Phase 2)
Sleep Bruxism (Phase 4)
Snoring (Phase 2)
Spasm (Phase 1/Phase 2)
Spinal Cord Injuries (Phase 4)
Squamous Cell Carcinoma of Head and Neck (Phase 1/Phase 2)
Stomach Neoplasms (Phase 2)
Stroke (Phase 4)
Stroke Rehabilitation (Phase 4)
Synkinesis (Phase 4)
Tachycardia, Ventricular (Phase 1)
Tardive Dyskinesia (Phase 1/Phase 2)
Temporomandibular Joint Disorders (Phase 1)
Tendinopathy (Phase 2)
Tennis Elbow (Phase 3)
Thoracic Outlet Syndrome (Phase 2)
Torticollis (Phase 4)
Traumatology (Phase 4)
Tremor (Phase 4)
Trigeminal Neuralgia (Phase 3)
Ulcer (Phase 2)
Urethral Diseases (Phase 2/Phase 3)
Urinary Bladder (Phase 4)
Urinary Bladder Diseases (Phase 2)
Urinary Bladder, Neurogenic (Phase 4)
Urinary Bladder, Overactive (Phase 4)
Urinary Incontinence (Phase 4)
Urinary Incontinence, Stress (Phase 4)
Urinary Incontinence, Urge (Phase 4)
Urinary Retention (Phase 2/Phase 3)
Urination Disorders (Phase 3)
Vaginismus (Phase 3)
Vision, Ocular (Phase 4)
Vitiligo (Phase 4)
Vulvar Diseases (Phase 4)
Vulvar Vestibulitis (Phase 4)
Vulvodynia (Phase 3)
Walking (Phase 2)
Wounds and Injuries (Phase 1)
Trial | Phase | Start Date | Organizations | Indications |
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